Embryology Research Today is a free monthly online journal that collates and summarizes the latest research about Embryology, including details on stem cells, reproduction, transplants, cloning.

Successful pregnancy following double-frozen embryo transfer in a patient with repeated implantation failure.

Esfandiari N, Coogan-Prewer J, Gotlieb L, Claessens EA, Casper RF

Toronto Centre for Advanced Reproductive Technology (TCART), Toronto, Canada.

OBJECTIVE: To report a case of successful singleton pregnancy following a novel technique of sequential double transfer of two groups of frozen embryos at the same developmental stage (8-cell) at 5 and 7 days after the LH surge to a patient with seven previous failed assisted reproductive technology (ART) cycles. DESIGN: Case report. SETTING: University of Toronto affiliated infertility clinic. PATIENT: A 27-year-old female with a three-year history of primary infertility. INTERVENTION: Double frozen embryo transfer of day-3 embryos two days apart in the luteal phase. MAIN OUTCOME MEASURE(S): Successful pregnancy. RESULT(S): Successful singleton pregnancy resulting in the delivery of healthy baby boy. CONCLUSION: To the best of our knowledge, the patient is the first to be treated successfully with double frozen-embryo transfer.

Published 17 December 2007 in Fertil Steril.
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