Embryology Research Today is a free monthly online journal that collates and summarizes the latest research about Embryology, including details on stem cells, reproduction, transplants, cloning.

Location of the embryo-transfer catheter guide before the internal uterine os improves the outcome of in vitro fertilization.

Abdelmassih VG, Neme RM, Dozortsev D, Abdelmassih S, Diamond MP, Abdelmassih R

Department of Reproductive Health, Clínica e Centro de Pesquisa em Reprodução Humana Roger Abdelmassih, São Paulo, Brazil. clinica@abdelmassih.com.br <clinica@abdelmassih.com.br>

The objective of this study was to assess whether positioning the embryo transfer (ET) catheter guide at the time of embryo expulsion, before or beyond the internal os, has an impact on IVF cycle outcome. We performed a retrospective study comparing IVF outcomes in relation to the ET guide position relative to the internal uterine os. We analyzed ultrasound-guided ETs in IVF-intracytoplasmic sperm injection (ICSI) cycles, performed with the tip of the ET catheter guide just before the internal os (group 1) and beyond the internal os (group 2). Implantation and pregnancy rates were significantly better in group 1 than in group 2, at 14.8% versus 11.8% and 57.3% versus 43.1, respectively. We conclude that passing the ET catheter guide beyond the internal os reduces implantation and pregnancy rates.

Published 13 August 2007 in Fertil Steril, 88(2): 499-503.
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